Frank Macfarlane Burnet

Frank Macfarlane Burnet (1899-1984): Australia's gift to immunology.

Comments on MacFarlane

The natural answer to this question, MacFarlane takes it, is “yes”. I do not propose to harp on the question of whether MacFarlane has the data right. Let us just assume, for the sake of argument, that he does. Let us further assume that his interpretation of the data is correct—i.e., that these judgments are assessments of the the whole clause and not simply of the prejacent. Granting all this...

Burnet of Australia.

'Darwin is the greatest of all scientists, greater even than Newton or Einstein, and I am quite certain that my own thinking has been more deeply influenced by the evolutionary concepts of Darwin than by anything else' (Burnet, 1966). 'Life must have begun as some particular configuration of atoms, an inconceivably tiny knot of molecular structure, which by some freak of circumstance was able t...

Comments on MacFarlane∗

The natural answer to this question, MacFarlane takes it, is “yes”. I don’t propose to harp on the question of whether MacFarlane has the data right. Let us just assume, for the sake of argument, that he does. Let us further assume that his interpretation of the data is correct—i.e., that these judgments are assessments of the the whole clause and not simply of the prejacent. Granting all this—...

Immunität, Immunity Selbst / Nichtselbst und das Gefahren – Modell der Immunologie Horror autotoxicus and the danger model of immunology

„Das herkömmliche Verständnis des Immunsystems ist, dass es Selbst von Nichtselbst unterscheidet“. Dieses Verständnis wurde 1950 von Sir Frank Macfarlane Burnet durch den Begriff Selbsttoleranz modifiziert. Das Selbst – Nichtselbst Modell wurde ursprünglich von Paul Ehrlich (http://de.wikipedia.org/wiki/Paul_Ehrlich) beschrieben. Er stellte infolge seiner Experimente an Tieren das biologische P...